Question #7357d
1 Answer
Antacids are non-Rx drugs used that neutralises stomach acidity.
Common examples are Alka-seltzer, Maalox, Gaviscon, Mylanta, Rolaids, Tums
Explanation:
Antacids are non-prescription medications (over-the-counter drugs) that neutralise stomach acidity. They are used to relieve the following symptoms:
- acid reflux (including regurgitation, bitter taste, persistent dry cough, pain when lying down, and trouble swallowing)
- heartburn caused by acid reflux (GERD)
- indigestion (pain on the upper portion of your gut that feels like gas or bloating)
Common Examples
- Alka-seltzers
- Maalox (contains Magnesium Hydroxide, and Aluminum Hydroxide)
- Gaviscon
- Mylanta
- Rolaids
- Tums
Mechanism of Action
Generally our stomachs have a pH of 1.5 to 3.5 however in some cases there may be excessive amounts of acids produced in the stomach. This may damage the lining of the stomach, and sometimes also the lining of the esophagus especially in people with acid reflux. Antacids act to counter this though a neutralization reaction between the acids of the stomach (HCl) and the major components of antacids, for example, Aluminum Hydroxide
Adverse Drug Reactions
- Antacids with magnesium may cause diarrhea, while those with aluminum, and calcium may cause constipation
- Long term use may also cause kidney stones
- Long term use of drugs with aluminum may cause osteoporosis
- Nausea, vomiting, and mental status change in cases of misuse
- Metabolic alkalosis (body become too basic)
Precautions and Contraindications
- Heart failure
- Chronic kidney disease, or kidney failure
- Children
Drug Interactions
- Inhibits absorption of tetracyclines (antibiotics) when taken together
