Question

What is the role of carbohydrate in maintaining glycoprotein stability?

Answer 1

Glycosylation is the extensively naturally occurring
covalent modification of a protein. which is essential for the growing polypeptide in protein synthesis(nescent protein converts into proper folded native protein).Carbohydrate moieties greatly aid in ligand and receptor recognition, binding affinity and cell cell interactions.

Explanation:

Carbohydrate molecules provide thermal stability towards heat during the denaturation process and resistance to proteolysis of the protein, hence promote protein folding.Nonglycosylated proteins have poorer thermal reversibility during thermal inactivation .Carbohydrates do not influence the conformation of the protein.