In IgG, what is the antigen binding site formed by?
1 Answer
Great question but hard to answer. The correct response is the genetic sequence for the VDJ recombination site for the specific B cell.
Explanation:
Each B cell that makes a single and specific antibody (IgG, IgE - etc.) has to be told what the protein will look like to create the greatest affinity to that antigen. DNA
Does this help?