Question #b6c38
1 Answer
Jan 27, 2018
The classic way would be to make the tolyl sulfonate ester.....
Explanation:
And so....
The sulfonate is an excellent leaving group that can be displaced by moderate nucleophiles....
When you do these reactions, you will not be a popular man/women. Toluene sulfonyl chlorides have a powerful, penetrating smell of rancid butter...and even with a lot of care, and an efficient hood, your neighbours will come around acomplaining....and you also have to use pyridine...