How many Good's buffer agents exist?

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Answer 1 · 2016-05-06T02:11:43

There are 20 Good buffers.

Named after Norman Good, they are all physiological buffers with $"p"K_a$ values ranging from 6.1 to 8.5.

The buffers, with their $"p"K_a$ values, are:

MES: $"2-("N"-morpholino)ethanesulfonic acid"$ , 6.15
ADA: $N"-(2-acetamido)iminodiacetic acid"$ , 6.62
PIPES: $"piperazine-"N,N′"-bis(2-ethanesulfonic acid)"$ , 6.82
ACES: $N"-(2-acetamido)-2-aminoethanesulfonic acid"$ , 6.88
MOPSO: $"3-("N"-morpholinyl)-2-hydroxypropanesulfonic acid"$ , 6.95
Cholamine chloride: $("CH"_3)_3 stackrel(+)("N")"CH"_2"CH"_2"NH"_2, "Cl"^"-"$ , 7.10
BES: $N,N"-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid"$ , 7.17
MOPS: $"3-("N"-morpholino)propanesulfonic acid"$ , 7.20
TES: $N"-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid"$ , 7.40
HEPES: $"4-(2-hydroxyethyl)-1-piperazinylethanesulfonic acid"$ , 7.48
DIPSO: $N,N"-bis(2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid"$ , 7.60
TAPSO: $"3-["N"-tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid"$ , 7.60
Acetamidoglycine: $"CH"_3"CONHNHCH"_2"COOH"$ , 7.7
POPSO: $"piperazine-"N,N′"-bis(2-hydroxypropanesulfonic acid)"$ , 7.85
HEPPSO: $"4-(2-hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid)"$ , 7.85
HEPPS: $"3-[4-(2-hydroxyethyl)-1-piperazinyl]propanesulfonic acid"$ , 8.00
Tricine: $N"-[tris(hydroxymethyl)methyl)]glycine"$ , 8.15
Glycinamide: $"NH"_2"CH"_2"CONH"_2$ , 8.20
Bicine: $N,N"-bis(2-hydroxyethyl)glycine"$ , 8.35
TAPS: $N"-tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid"$ , 8.44