Question

Please,explain me what is lock and key theory of enzyme?

Answer 1

This model supports that a specific substrate(key) can be inserted into a particular enzyme(lock). Means that enzyme are subtrate-specific.

Explanation:

Lock and Key Model:

Emil Fischer proposed this model in `1894` . According to this model:

• As one specific key can open only a specific lock, just like that a specific enzyme can convert only one particular substrate into product(s).
• This model supports that an active site is a rigid structure.
• And active site play a role of template only. So, there is no modification in the active site before, during or after the reaction.
  

`Side` `"Information":`
This model was further improved by Koshland and he named the new model as "Induced fit model" which was practically more accepted.

Hope it helps...