What is bretylium tosylate used for?
1 Answer
Jul 17, 2016
Bretylium tosylate was used an antiarrhythmic agent.
It was originally used for the treatment of ventricular fibrillation.
However, it is no longer available because the manufacturers could not provide a reliable supply of the drug.
The structure of bretylium tosylate [(o-BRomobenzyl)EThyldimethYLammonIUM
p-toluenesulfonate] is
You can probably imagine the difficulty of carrying out an electrophilic aromatic substitution that puts two bulky groups next to each other on a benzene ring.
