Question

What is the Henderson-Hasselbalch equation?

Answer 1

The Henderson-Hasselbalch equation is an equation that determines the pH pf a buffer.

Acid Buffers

For a solution of a weak acid and its conjugate base,

HA + H₂O ⇌ H₃O⁺ + A⁻

pH = `pK_a + log("[A⁻]"/"[HA]")`

Base Buffers

For a solution of a weak base and its conjugate acid,

B+ H₂O ⇌ BH⁺ + OH⁻

pOH = `pK_b + log("[BH⁺]"/"[B]")`