The cotangent is the reciprocal of the tangent:
#cot(theta) = -4/6#
Use #1 + tan^2(theta) = sec^2(theta)# to obtain the secant and the cosine; we know that both the secant and the cosine must be negative because we are given #sin(theta) > 0#
#1 + ((-6)/4)^2 = sec^2(theta)#
#sec^2(theta) = 16/16 + 36/16#
#sec^2(theta) = 52/16#
#sec(theta) = -sqrt52/4#
#cos(theta) = (-4sqrt52)/52#
#sin(theta) = (-6/4)cos(theta)#
#sin(theta) = (6sqrt52)/52#
#csc = sqrt(52)/6#