Question

How does an SN2 reaction affect stereochemistry?

Answer 1

In an `"S"_"N"2` reaction, the stereochemistry of the product is inverted compared to that of the substrate.

An `"S"_"N"2` reaction is a backside attack. The nucleophile attacks the electrophilic center on the side that is opposite to the leaving group.

During a backside attack, the stereochemistry at the carbon atom changes. There is inversion of configuration.

Here’s a video on `"S"_"N"2` stereochemistry.