What is hydroboration oxidation in alkenes?

1 Answer
Jul 20, 2015

Hydroboration-oxidation is a method of making alcohols from alkenes.

Explanation:

It involves the addition of BH3 to an alkene, followed by oxidation with alkaline hydrogen peroxide to form an alcohol.

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The reaction is a Markovnikov addition of BH3 to the alkene

On oxidation of the boron intermediate, the OH group ends up on the less substituted carbon.

This is opposite to the position of the OH group in the acid-catalyzed Markovnikov addition of water to an alkene, so the reaction is often called the anti-Markovnikov addition of water to an alkene.